Immunization Integration Program

The Immunization Integration Program (IIP) strives to improve the way immunization data is shared, managed, and used to promote public health. The IIP is a partnership between AIRA, the Healthcare Information and Management Systems Society (HIMSS), and Drummond Group, in cooperation with the Centers for Disease Control and Prevention's National Center for Immunization and Respiratory Diseases.

The IIP aims to improve interoperability between immunization data exchange partners by bringing together:

  • Public Health Immunization Information System (IIS) Managers and Immunization Program Managers
  • Health Information Technology (IT) Developers (e.g., electronic health records [EHRs])
  • IIS Technology Partners
  • Clinicians
  • Health Information Exchanges (HIEs)
  • Other Key Collaborators

A seamless, accurate, and compliant exchange of immunization information will help health and public health leaders improve outcomes, lower costs, and create more robust vaccination programs.

The IIP advances its goals through two initiatives:

  1. Testing and Recognition – This initiative helps EHRs and other clinical systems adopt and confirm immunization-related capabilities, allowing EHRs and IIS to share high-quality information clinicians need to make important immunization decisions.
  2. Collaborative – This initiative brings all IIP partners together to develop and implement innovative solutions that improve interoperability and immunization information sharing.

Testing and Recognition

The IIP Testing and Recognition initiative helps EHR developers validate their immunization-focused capabilities and acknowledges their ability to exchange immunization data. This program is approved by the Office of the National Coordinator for Health Information Technology (ONC) as an alternative method for transmission to immunization registries certification criteria. Testing and recognition are offered at no-cost to the participating vendor.

EHRs must demonstrate immunization capabilities to achieve IIP recognition. Components include:

  • Registering and identifying patients
  • Managing cohorts
  • Managing adverse events
  • Managing external query, response, and reconciliation
  • Administering and reporting immunization
  • Providing patient access
  • Managing information for clinical decision making
  • Managing inventory

Testing will help EHR developers learn whether their products meet ONC and IIP requirements. Clinicians can also use this information to have more informed discussions with EHR vendors and evaluate their solutions.

Benefits of Testing and Recognition

EHRs that achieve IIP recognition will be featured in IIP-related materials by AIRA and HIMSS. In addition, these organizations will be highlighted on the HIMSS website and through media coverage. They will also receive a marketing toolkit, a Seal of Recognition for their website, prominent logo visibility on the IIP website, and recognition signage at the HIMSS Global Health Conference & Exhibition.

Continue learning about the IIP Testing and Recognition initiative. Get an overview of testing requirements, download the IIP test plan, apply to participate, and learn more about usability guidance.


By giving key partners a seat at the table, the IIP Collaborative offers a forum to help increase awareness of interoperability challenges, identify priority areas, create solutions to meet the most pressing needs, and encourage adoption of solutions that can make the biggest impact.

The IIP conducts a comprehensive process to prioritize issues for the Collaborative to address. The steps to the approach include:

  • Research each challenge to learn different perspectives, identify current efforts, recommend solutions, and understand any barriers to adoption.
  • Assess each challenge based on their impact on public health, safety and quality, the priorities of each stakeholder, and the feasibility of potential solutions to create positive change.
  • Prioritize key issues to address, gather additional information, share the top issues with constituents, and develop rollout plans for each identified issue.

In November 2021, the IIP announced four top priorities for improving immunization interoperability, data exchange, and management in 2022:

  1. Using bulk queries to access IIS data. IIS receive twice as many queries as submissions on average, and sometimes partners cannot access the data they need in a timely fashion. Partners would benefit from a standardized way to access large amounts of IIS data for their patients/members.
  2. Validating data and addressing reasons for IIS rejections. When inaccurate or inconsistent information, such as birth date discrepancies, missing fields, or dates entered in the future are present, an IIS may reject immunization messages. Validating data prior to submission can help solve this challenge.
  3. Improving the capture of race and ethnicity. Race and ethnicity are frequently missing in reports to IIS and answers of “unknown” are common. Improving the capture and submission of these data will support and improve vaccine equity.
  4. Regularly updating code sets. Out-of-sync code sets—such as National Drug Codes for the annual influenza vaccination—between immunization data exchange partners inhibit interoperability and can prevent patients’ vaccinations from being recorded properly.

Continue learning about the IIP Collaborative. View current priorities, activities, and solutions.

Benefits of the IIP

Improving interoperability between IIS and EHRs brings concrete benefits to multiple entities in health care and public health.

  • Clinicians are able to provide the right immunization for the right patient at the right time.
  • IIS and immunization program managers have the data they need to monitor and improve immunization rates and inform public health programs.
  • EHRs and other health IT developers improve information sharing with IIS and achieve higher levels of data quality and standardization.
  • HIEs are able to offer robust immunization-related services to their members by leveraging existing connections and inherent functionalities.
  • IIS technology partners will know more about IIP participants’ pain points and Centers for Disease Control and Prevention recommendations.

Continue Learning About the IIP